7253. Phenoxazine

Nomenclature

CAS number: 135-67-1
Phenazoxine.
C12H9NO; mol wt 183.21.
C 78.67%, H 4.95%, N 7.65%, O 8.73%.

Description and references

Prepn from 2-aminophenol and 2-aminophenol-HCl: Kehrmann, Neil, Ber. 47, 3107 (1903); de Antoni, Bull. Soc. Chim. Fr. 1963, 2871; by heating 2-amino-2′-hydroxydiphenyl ether in a sealed tube at 270-280° for 40 hrs: Cullinane et al., J. Chem. Soc. 1934, 718.

Chemical structure

Properties

Leaflets from alc, mp 156°. Freely sol in abs methanol, ethanol, ether, CHCl3, benzene. Sparingly sol in petr ether.

Derivative

10-Acetylphenoxazine.
C14H11NO2; mol wt 225.24.
C 74.65%, H 4.92%, N 6.22%, O 14.21%.

Properties

Prisms, mp 142°. Sparingly sol in hot water; sol in alc; freely sol in glacial acetic acid.