7290. Phenylglyceryl Ether

Nomenclature

CAS number: 538-43-2
3-Phenoxy-1,2-propanediol; 1,2-dihydroxy-3-phenoxypropane; glycerol α-monophenyl ether; Antodyne.
C9H12O3; mol wt 168.19.
C 64.27%, H 7.19%, O 28.54%.

Description and references

Prepd from phenol and 3-chloro-1,2-propylene carbonate: Smith, US 2967892 (1961 to Dow). Toxicity study: Hine et al., J. Pharmacol. Exp. Ther. 97, 414 (1949).

Chemical structure

Properties

Crystals, mp 50-52°, bp0.6 129-142°. Sol in water, alcohol. LD50 i.p. in mice: 1280 mg/kg (Hine).