7323. Phillyrin

Nomenclature

CAS number: 487-41-2
[1S-(1α,3aα,4β,6aα)]-4-[4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl-β-d-glucopyranoside; phyllyrin; phillyroside; forsythin.
C27H34O11; mol wt 534.55.
C 60.67%, H 6.41%, O 32.92%.

Description and references

From bark of Phillyrea latifolia L., and allied Oleaceae: Campona, Ann. 24, 242 (1837); Eijkman, Rec. Trav. Chim. 5, 127 (1886); Kramer, Compt. Rend. 196, 814 (1933); Sosa, Bull. Soc. Chim. Biol. 29, 918 (1947). Structure: Kaku et al., J. Pharm. Soc. Jpn. 59, 248 (1939); M. Chiba et al., Chem. Pharm. Bull. 25, 3435 (1977).

Chemical structure

Derivative

α-Form.

Properties

Needles from dil alc, mp 154-155°. [α]D +48.4° (alcohol).

Derivative

β-Form.

Properties

Needles, mp 184-185°. [α]D +48.5° (alcohol).