Mixture of higher (C24 to C34) primary aliphatic alcohols purified from wax of sugar cane, Saccharum officinarum L., Gramineae. Composed of octacosanol (60-70%), triacontanol (10-15%), dotriacontanol (5-10%), hexacosanol (3-8%), heptacosanol, nonacosanol, tetratriacontanol, and tetracosanol. Prepn: L. Granja et al., WO 9407830; eidem, US 5856316 (1994, 1999 both to Dalmar). Clinical pharmacology: I. Gouni-Berthold, H. K. Berthold, Am. Heart J. 143, 356 (2002). Antiplatelet effects: M. L. Arruzazabala et al., Clin. Exp. Pharmacol. Physiol. 29, 891 (2002). Review of clinical studies: M. Janikula, Altern. Med. Rev. 7, 203-217 (2002); and comparison with plant sterols and stanols: J. T. Chen et al., Pharmacotherapy 25, 171-183 (2005).
Antilipemic.
Antilipemic