7781. Prolintane

Nomenclature

CAS number: 493-92-5
1-[1-(Phenylmethyl)butyl]pyrrolidine; 1-(α-propylphenethyl)pyrrolidine; 1-phenyl-2-pyrrolidylpentane; phenylpyrrolidinopentane; SP-732.
C15H23N; mol wt 217.35.
C 82.89%, H 10.67%, N 6.44%.

Description and references

Prepn: GB 807835; Seeger, Kottler, DE 1093799 (1959, 1960 both to Thomae), C.A. 55, 19950c (1961). Pharmacological studies: R. Kadatz, E. P"otzsch, Arzneim.-Forsch. 7, 344 (1957); K. Takagi et al., Oyo Yakuri 5, 5 (1971), C.A. 76, 94575k (1972).

Chemical structure

Properties

bp0.5 105°; bp16 153°.

Derivative

Hydrochloride.

Nomenclature

CAS number: 1211-28-5
Katovit (Thomae); Promotil (Boehringer, Ing.).
C15H23N.HCl; mol wt 253.81.
C 70.98%, H 9.53%, N 5.52%, Cl 13.97%.

Properties

Crystals from methyl ether, mp 133-134°. LD50 orally in mice: 257 mg/kg (Kadatz, P"otzsch).

Therapeutic Category

CNS stimulant; antidepressant.

Keywords

Antidepressant; CNS Stimulant