7796. Propallylonal
Nomenclature
CAS number: 545-93-7
5-(2-Bromo-2-propenyl)-5-(1-methylethyl)-2,4,6(1H,3H,5H)pyrimidinetrione; 5-(2-bromoallyl)-5-isopropylbarbituric acid; Noctal (UCB). C10H13BrN2O3; mol wt 289.13.
C 41.54%, H 4.53%, Br 27.64%, N 9.69%, O 16.60%.
Description and references
Prepn: US 1622129 (1927); cf. Herzog, Arch. Pharm. 263, 216 (1925). Acute toxicity: Maloney, J. Pharmacol. Exp. Ther. 42, 267 (1931).
Properties
Crystals. mp 177-179°. Slightly bitter taste. Slightly sol in water; freely sol in alcohol, glacial acetic acid, acetone, alkalies. Sparingly sol in ether, chloroform, benzene. MLD orally in rabbits: 300-350 mg/kg (Maloney).Note
This is a controlled substance (depressant): 21 CFR, 1308.13.Therapeutic Category
Sedative, hypnotic.
Keywords
Sedative/Hypnotic; Barbituric Acid Derivatives