7836. Propoxur

Nomenclature

CAS number: 114-26-1
2-(1-Methylethoxy)phenol methylcarbamate; o-isopropoxyphenyl N-methylcarbamate; aprocarb; Bay 39007; Bay 9010; Baygon (Bayer); Bifex (Provet); Blattanex (Bayer); Propyon (Makhteshim-Agan); Suncide (Bayer); Unden (Bayer).
C11H15NO3; mol wt 209.24.
C 63.14%, H 7.23%, N 6.69%, O 22.94%.

Description and references

Prepn: US 3111539 (1963 to Bayer; Chemagro Corp.). Properties: W. Behrenz, E. Boecker, Pflanzenschutz-Nachr. Bayer (Ger. Ed.) 18, 53 (1965). Toxicity data: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969). Efficacy vs fleas and ticks in domestic animal collars: R. G. Hughes, Vet. Med. Rev. 1, 80 (1985). Teratogenicity study: K. D. Courtney et al., J. Environ. Sci. Health B20, 373 (1985). Environmental fate and LC/MS determn: L. Sun, H. K. Lee, J. Chromatogr. A 1014, 153 (2003).

Chemical structure

Properties

Minute crystals, mp 91.5°. Dec at high temp forming methyl isocyanate. Sol in methanol, acetone and many organic solvents, but only slightly sol in cold hydrocarbons. Water soly about 0.2% at 20°. Unstable in highly alkaline media. LD50 orally in male, female rats: 83, 86 mg/kg (Gaines).

Caution

Potential symptoms of overexposure are miosis, blurred vision; sweating, salivation; abdominal cramps, nausea, diarrhea, vomiting, headache, weakness, muscle twitching. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 266.

Use

Insecticide.