7872. Propyzamide

Nomenclature

CAS number: 23950-58-5
3,5-Dichloro-N-(1,1-dimethyl-2-propynyl)benzamide; pronamid; RH-315; Kerb (Dow AgroSci.).
C12H11Cl2NO; mol wt 256.13.
C 56.27%, H 4.33%, Cl 27.68%, N 5.47%, O 6.25%.

Description and references

Selective pre-emergence herbicide. Prepn: B. W. Horrom et al., ZA 6800090; eidem, US 3534098; US 3640699 (1969, 1970, 1972 all to Rohm & Haas). Activity: K. L. Viste et al., Science 167, 280 (1970); C. Swithenbank et al., J. Agric. Food Chem. 19, 417 (1971). Metabolism: R. Y. Yih et al., Weed Sci. 18, 604 (1970); R. Y. Yih, C. Swithenbank, J. Agric. Food Chem. 19, 314, 320 (1971); J. D. Fisher, ibid. 22, 606 (1974). Carcinogenicity study: M. D. Reuber, Environ. Res. 23, 1 (1980).

Chemical structure

Properties

White solid, mp 155-156°. Soly in water at 25°: 15 ppm. Sol in aliphatic, aromatic solvents. Vapor pressure at 25°: 8.5 × 10-5 mm Hg. LD50 in male, female rats (mg/kg): 8350, 5620 orally (Viste).

Use

Herbicide.