7952. Py-Phe

Nomenclature

CAS number: 199612-75-4
N-[1-Oxo-4-(1-pyrenyl)butyl]-l-phenylalanine; N-(1-phenylalanine)-4-(1-pyrene)butyramide.
C29H25NO3; mol wt 435.51.
C 79.98%, H 5.79%, N 3.22%, O 11.02%.

Description and references

Photoactivated chemical protease. Prepn: C. V. Kumar, A. Buranaprapuk, Angew. Chem. Int. Ed. 36, 2085 (1997). Site specificity: idem et al., Proc. Natl. Acad. Sci. USA 95, 10361 (1998).

Chemical structure

Properties

ε 42600 M-1cm-1 at 343 nm.

Use

Photocleavage probe.