8013. Pyrrocaine

Nomenclature

CAS number: 2210-77-7
N-(2,6-Dimethylphenyl)-1-pyrrolidineacetamide; 1-pyrrolidineaceto-2′,6′-xylidide; 2-(1-pyrrolidinyl)-2′,6′-acetoxylidide; 1-pyrrolidinoaceto-2,6-dimethylanilide; EN-1010; NSC-52644; Endocaine (Endo); Dynacaine.
C14H20N2O; mol wt 232.32.
C 72.38%, H 8.68%, N 12.06%, O 6.89%.

Description and references

Prepn: Schlesinger, Gordon, US 2813861 (1957 to Endo); L"ofgren et al., Acta Chem. Scand. 11, 1724 (1957).

Chemical structure

Properties

Crysts from hexane or petr ether + dibutyl ether, mp 83°.

Derivative

Hydrochloride.

Nomenclature

CAS number: 2210-64-2
C14H20N2O.HCl; mol wt 268.78.
C 62.56%, H 7.88%, N 10.42%, O 5.95%, Cl 13.19%.

Properties

Crystals from isopropanol, mp 205°. Soluble in water, alcohol, isopropyl alcohol. Practically insol in chloroform, ether.

Therapeutic Category

Anesthetic (local).

Keywords

Anesthetic (Local)