8048. Quinaldine Blue

Nomenclature

CAS number: 2768-90-3
1-Ethyl-2-[3-(1-ethyl-2(1H)-quinolinylidene)-1-propenyl]quinolinium chloride; bis[1-ethylquinoline-(2)]trimethinecyanine chloride; 1,1′-diethyl-2,2′-trimethinequinocyanine chloride; pinacyanol chloride; Vernitest Reagent.
C25H25ClN2; mol wt 388.93.
C 77.20%, H 6.48%, Cl 9.12%, N 7.20%.

Description and references

Prepn: Fischer, J. Prakt. Chem. 98, 204 (1918). Properties and use as histological stain: F. Proescher, Proc. Soc. Exp. Biol. Med. 31, 79 (1933); H. P. Klinger et al., Stain Technol. 46, 43 (1971); R. K. J. Narayan, ibid. 55, 9 (1980).

Chemical structure

Properties

Bright blue-green alcohol-containing prisms or needles from alcohol. Drying at 110° expels alcohol of crystn. Dec at ≈263°. Moderately sol in water with a violet-red color, in alcohol with a blue color. Solns are dichroic.

Use

Histological stain (chromosomes).