8055. Quinestrol

Nomenclature

CAS number: 152-43-2
(17α)-3-(Cyclopentyloxy)-19-norpregna-1,3,5(10)-trien-20-yn-17-ol; 17α-ethinylestradiol 3-cyclopentyl ether; W-3566; Estrovis (G"odecke).
C25H32O2; mol wt 364.52.
C 82.37%, H 8.85%, O 8.78%.

Description and references

Prepn: Ercoli, Gardi, Chem. Ind. (London) 1961, 1037; Ercoli, US 3159543; Ercoli et al., US 3231567 (1964, 1966, both to Vismara).

Chemical structure

Properties

Crystals, mp 107-108°. [α]D25 +5° (c = 0.5 in dioxane).

Therapeutic Category

Estrogen.

Keywords

Estrogen; Steroidal