Description and references
Isoln from cinchona bark (cortex chinae): Hlasiwetz, Ann. 111, 182 (1859); Liebermann, Giesel, Ber. 16, 926 (1883). A mixture of three glycosides, 60% A,
5% B and 30% C: Tschesche et al., Ann. 667, 151 (1963).
Derivative
Glycoside A.
Nomenclature
Quinovic acid β-d-quinovoside. C
36H
56O
9; mol wt 632.82.
C 68.33%, H 8.92%, O 22.75%.
Properties
Crystals from methanol + water, mp 237-238°. [α]D21 +57 ± 2° (ethanol).Derivative
Glycoside B.
Nomenclature
Cincholic acid β-d-quinovoside. C
36H
56O
9; mol wt 632.82.
C 68.33%, H 8.92%, O 22.75%.
Properties
Crystals from methanol + water, mp 193-195°. [α]D19 +78 ± 3° (c = 0.78
in ethanol).Derivative
Glycoside C.
Nomenclature
Quinovic acid β-d-glucoside. C
36H
56O
10; mol wt 648.82.
C 66.64%, H 8.70%, O 24.66%.
Properties
Crystals from methanol + water, mp 247-250°. [α]D20 +62 ±2° (ethanol).