Nomenclature
CAS number: 25395-22-6
[2-(Aminocarbonyl)phenoxy]acetic acid;
o-(carbamylphenoxy)acetic acid; α-(2-carbamoylphenoxy)acetic acid.
C
9H
9NO
4; mol wt 195.17.
C 55.39%, H 4.65%, N 7.18%, O 32.79%.
Description and references
Prepn: Merriman, J.
Chem. Soc. 103, 1838 (1913); Tzofin, J. Gen. Chem. USSR 3, 17 (1933);
Klosa, Arch. Pharm. 288, 389 (1955); Izumi et al., JP 56 874 (1956 to Yoshitomi).
Pharmacokinetics and efficacy: D. Loew et al., Int. J. Clin. Pharmacol. Ther. Toxicol. 30, 509 (1992).
Properties
Crystals, mp 221°. Sol in aq alkali.Derivative
Sodium salt.
Nomenclature
CAS number: 3785-32-8
Salizell (amp.) (Byk Gulden).
C
9H
8NNaO
4; mol wt 217.15.
C 49.78%, H 3.71%, N 6.45%, Na 10.59%, O 29.47%.
Properties
Crystals, mp 212-215°.Derivative
Diethylamine salt.
Nomenclature
Akistin (Nycomed). C
13H
22N
2O
4; mol wt 270.32.
C 57.76%, H 8.20%, N 10.36%, O 23.67%.
Therapeutic Category
Analgesic; anti-inflammatory; antipyretic.
Keywords
Anti-inflammatory (Nonsteroidal); Salicylic Acid Derivatives; Antipyretic; Analgesic; Non-opioids; Salicylic Acid Derivatives