Dried rhizome and roots of Sanguinaria canadensis L., Papaveraceae. Habit. North America. Constit. Sanguinarine, chelerythrine, protopine, homochelidonine, resin. An extract of Sanguinaria canadensis has been used in cough syrup; used experimentally as toothpaste base, in gingivitis and in periodontal disease: P. A. Ladanyi, US 4145412 (1979 to Vipont Chem. Co.).