8823. Streptodornase

Nomenclature

CAS number: 37340-82-2
Streptococcal deoxyribonuclease.

Description and references

DNAase produced by various strains of β-hemolytic streptococci. Identification in culture medium: W. S. Tillett et al., Proc. Soc. Exp. Biol. Med. 68, 184 (1948); M. McCarty, J. Exp. Med. 88, 181 (1948). Purification: J. H. Mowat et al., US 2753291 (1956 to Am. Cyanamid). Clinical use with streptokinase in wound debridement: J. Poulsen et al., Acta Chir. Scand. 149, 245 (1983).

Derivative

Mixture with streptokinase.

Nomenclature

CAS number: 8048-16-6
Ernodasa (ERN); Varidase (Lederle).

Therapeutic Category

Debriding agent.

Keywords

Debriding Agent