8856. Strychnine N6-Oxide

Nomenclature

CAS number: 7248-28-4
Strychnidin-10-one 19-oxide; Genostrychnine.
C21H22N2O3; mol wt 350.41.
C 71.98%, H 6.33%, N 7.99%, O 13.70%.

Description and references

Prepn: Pictet, Mattison, Ber. 38, 2782 (1905); Bailey, Robinson, J. Chem. Soc. 1948, 703; Zellner, US 2758113 (1956 to Donau-Pharmazie).

Chemical structure

Properties

Monoclinic prisms from water, dec 207°. pK 5.17. Freely sol in alc, glacial acetic acid, chloroform; fairly sol in water; sparingly sol in benzene. Practically insol in ether, petr ether.

Derivative

Hydriodide.

Properties

Light yellow plates from hot water, dec 253°.

Derivative

Nitrate.

Properties

Small transparent prisms from water, dec 250°.