8987. Sulphan Blue

Nomenclature

CAS number: 129-17-9
N-[4-[[4-(Diethylamino)phenyl](2,4-disulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-N-ethylethanaminium inner salt, sodium salt; C.I. Acid Blue 1; [4-[α-[p-(diethylamino)phenyl]-2,4-disulfobenzylidene]-2,5-cyclohexadien-1-ylidene]diethylammonium hydroxide inner salt sodium salt; anhydro-4,4′-bis(diethylamino)triphenylmethanol-2″,4″-disulfonic acid monosodium salt; C.I. Food Blue 3; C.I. 42045; Disulphine Blue (Zeneca).
C27H31N2NaO6S2; mol wt 566.66.
C 57.23%, H 5.51%, N 4.94%, Na 4.06%, O 16.94%, S 11.32%.

Description and references

Prepn from 4-formylbenzene-1,3-disulfonic acid and diethylaniline: Colour Index vol. 4 (3rd ed., 1971) p 4382.

Chemical structure

Properties

Violet powder. One gram dissolves in 20 ml water at 20°. Dilute aq solns are blue and turn yellow upon the addition of concd hydrochloric acid. In the absence of strong acid or caustic the blue color is stable over a wide pH range. Partly sol in alcohol.

Derivative

2,5-Disulfophenyl isomer.

Nomenclature

CAS number: 68238-36-8
Isosulfan blue; Lymphazurin (Pharmascience).

Use

Coloring medicinal products; in dyeing and printing wool, silk.

Therapeutic Category

Isosulfan blue as diagnostic aid (lymphangiography).

Keywords

Isosulphan Blue: Diagnostic Aid