9147. Tenonitrozole

Nomenclature

CAS number: 3810-35-3
N-(5-Nitro-2-thiazolyl)-2-thiophenecarboxamide; 2-(α-thenoylamino)-5-nitrothiazole; thenitrazole; TC-109; Atrican (Innotech); Moniflagon (Dieetzout).
C8H5N3O3S2; mol wt 255.27.
C 37.64%, H 1.97%, N 16.46%, O 18.80%, S 25.12%.

Description and references

Prepd from 2-thenoyl chloride and 2-amino-5-nitrothiazole: FR M715 (1961 to Chantereau), C.A. 59, 7533g (1963).

Chemical structure

Properties

Crystals from dioxane or DMF, mp 255-256°.

Therapeutic Category

Antiprotozoal (Trichomonas); antifungal.

Keywords

Antifungal (Synthetic); Antiprotozoal (Trichomonas)