9230. Tetramethylurea

Nomenclature

CAS number: 632-22-4
N,N,N′,N′-Tetramethylurea; tetramethylcarbamide; TMU; Temur.
C5H12N2O; mol wt 116.16.
C 51.70%, H 10.41%, N 24.12%, O 13.77%.

Description and references

Prepn: Lawson, Croom, J. Org. Chem. 28, 232 (1963). Review of prepn, manuf, properties and use as solvent and as reagent: Lüttringhaus, Dirksen, Angew. Chem. Int. Ed. 3, 260 (1964).

Chemical structure

Properties

Liquid with faint, pleasant odor, bp 176.5°, bp740 174.5°, bp12 63-64°. mp -1.2°. Flash pt ≈75°C. d420 0.9687. nD25 1.4493. Dipole moment: 3.47 D in benzene. pKb 2. uv max: 217.5 nm (ε 1940). Miscible with water and with all common organic solvents including petr ether. LD50 i.v. in rats: 1.1 g/kg (Lüttringhaus, Dirksen).

Use

As solvent and reagent.