9335. Thioglycerol

Nomenclature

CAS number: 96-27-5
3-Mercapto-1,2-propanediol; α-monothioglycerol; thioglycerin.
C3H8O2S; mol wt 108.16.
C 33.31%, H 7.46%, O 29.58%, S 29.65%.

Description and references

Prepn: L. Carius, Ann. 124, 221 (1862); B. Sjberg, Ber. 75, 13 (1942). Use in fast atom bombardment MS: C. Dass, J. Mass Spectrom. 31, 77 (1996); as antioxidant in cell culture media: M. Brielmeier et al., Nucleic Acids Res. 26, 2082 (1998).

Chemical structure

Properties

Yellowish, very viscous, hygroscopic liquid; slight sulfidic odor. bp1 100-101°. d 1.246. nD20 1.527. Flash point, closed cup: 235°F (113°C). Slightly sol in water; miscible with alcohol. Insol in ether.

Use

Antioxidant preservative; reagent in analytical chemistry, cell culture research. Matrix substrate in fast atom bombardment mass spectrometry.