Low molecular weight heparin prepared by enzymatic depolymerization of porcine mucosal heparin with heparinase from Flavobacterium heparinum. Approx mol wt 4900 Da. Manufacturing process: J. I. Nielsen, P. B. Ostergaard, EP 244236; J. I. Nielsen, US 5106734 (1987, 1992 both to Novo). Pharmacokinetics: P. C. Pedersen et al., Thromb. Res. 61, 477 (1991). Multicenter clinical trial: A. Liezorovicz et al., Br. J. Surg. 78, 412 (1991).
Antithrombotic.
Antithrombotic