9603. Triaziquone

Nomenclature

CAS number: 68-76-8
2,3,5-Tris(1-aziridinyl)-2,5-cyclohexadiene-1,4-dione; 2,3,5-tris(1-aziridinyl)-p-benzoquinone; 2,3,5-tris(aziridino)-1,4-benzoquinone; 2,3,5-tris(ethyleneimino)benzoquinone; trenimon; Bayer 3231.
C12H13N3O2; mol wt 231.25.
C 62.33%, H 5.67%, N 18.17%, O 13.84%.

Description and references

Polyfunctional alkylating agent. Prepn: Gauss, Domagk, US 2976279 (1961 to Schenley). Review of biochemical, physiological and genetic effects: G. Obe, B. Beek, Mutat. Res. 65, 21-70 (1979); of structure and chemical reactivity: P. Rademacher, G. Obe, ibid. 340, 37-49 (1995).

Chemical structure

Properties

Purple acicular crystals from ethyl acetate, mp 162.5-163°. Sparingly sol in cold water; sol in acetone, benzene, chloroform, ethyl acetate, methanol and warm acetic acid.

Use

Alkylating reagent in mutation research.