9661. Tridihexethyl Iodide
Nomenclature
CAS number: 125-99-5
γ-Cyclohexyl-N,N,N-triethyl-γ-hydroxybenzenepropanaminium
iodide; (3-cyclohexyl-3-hydroxy-3-phenylpropyl)triethylammonium iodide; 3-diethylamino-1-cyclohexyl-1-phenyl-1-propanol ethiodide; 3-diethylamino-1-phenyl-1-cyclohexyl-1-propanol ethiodide; α-(2-diethylaminoethyl)-α-phenylcyclohexanemethanol ethiodide; propethonum iodide; tridihexethide; 921 C; Claviton. C21H36INO; mol wt 445.42.
C 56.63%, H 8.15%, I 28.49%, N 3.14%, O 3.59%.
Description and references
Anticholinergic. Prepn: Lobby, US 2913494 (1959 to Am. Cyanamid).
Properties
Bitter crystals, mp 179-184°. Solubility in water at 25°: 1.1 g/100 ml. Freely sol in alc, chloroform. Very slightly sol in ether. pH of a 1% aq soln 5.5-7.Note
The name Pathilon previously used for the iodide is now used for tridihexethyl chloride.Therapeutic Category
Antispasmodic.
Keywords
Antimuscarinic; Antispasmodic