9662. Tridiphane

Nomenclature

CAS number: 58138-08-2
2-(3,5-Dichlorophenyl)-2-(2,2,2-trichloroethyl)oxirane; Dowco 356.
C10H7Cl5O; mol wt 320.43.
C 37.48%, H 2.20%, Cl 55.32%, O 4.99%.

Description and references

Prepn: L. D. Markley, E. J. Norton, DE 2519073; eidem, US 4211549 (1975, 1980 both to Dow). Herbicidal activity: J. A. Jagschitz, Proc. Annu. Meet. Northeast. Weed Sci. Soc. 39, 274 (1985); D. B. Vitolo et al., ibid. 40, 272 (1986). Field trial in combination with atrazine, q.v.: P. J. Dryden, M. J. Watson, Proc. 38th N. Z. Weed Pest Control Conf. 1985, 191. Mechanism of action: G. L. Lamoureux, D. G. Rusness, Pestic. Biochem. Physiol. 26, 323 (1986). Metabolism in mouse: J. Magdalou, B. D. Hammock, Toxicol. Appl. Pharmacol. 91, 439 (1987). Toxicological studies: T. R. Hanley et al., Fundam. Appl. Toxicol. 8, 179 (1987); J. A. John-Greene et al., Toxicology 43, 325 (1987).

Chemical structure

Properties

Yellow oil, nD25 1.5720. LD50 for technical grade (89-91% pure) in male, female mice, male, female rats (mg/kg): ≈1200, ≈740, 1700-2300, 1500-1900 orally (Hanley).

Use

Herbicide.