9773. Tropacine

Nomenclature

CAS number: 6878-98-4
α-Phenylbenzeneacetic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; 1αH,5αH-tropan-3α-ol diphenylacetate; diphenylacetic acid 3α-tropanyl ester; 3α-tropanyl diphenylacetate; tropine diphenylacetate.
C22H25NO2; mol wt 335.44.
C 78.77%, H 7.51%, N 4.18%, O 9.54%.

Description and references

Anticholinergic. Prepd from tropine and diphenylacetyl chloride: CH 202181 (1939 to Ciba), C.A. 33, 89228 (1939); Friess et al., Toxicol. Appl. Pharmacol. 2, 574 (1960).

Chemical structure

Derivative

Hydrochloride.

Properties

Crystals from chloroform + ether, mp 217-218°.

Therapeutic Category

Antiparkinsonian

Keywords

Antiparkinsonian