10125. Zilpaterol
Nomenclature
CAS number: 119520-05-7
(6R,7R)-rel-4,5,6,7-Tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]imidazo[4,5,1-jk][1]benzazepin-2(1H)-one; (±)-trans-4,5,6,7-tetrahydro-7 hydroxy-6-(isopropylamino)imidazo[4,5,1-jk][1]benzazepin-2(1H)-one; RU-42173. C14H19N3O2; mol wt 261.32.
C 64.35%, H 7.33%, N 16.08%, O 12.25%.
Description and references
β-Adrenergic agonist. Prepn: D. Fréchet et al., FR 2534257; eidem, US 4585770 (1984, 1986 both to Roussel Uclaf). Effects on growth performance and carcass characteristics of steers: A. Plascencia et al., Proc. West. Sect. Am. Soc. Anim. Sci. 50, 331-334 (1999). GC/MS determn in commercial feeds: B. Bocca et al., J. Chromatogr. B 783, 141 (2003); in calf eye: idem et al., J. AOAC Int. 86, 8 (2003). Residue analysis in cattle and pigs: C. S. Stachel et al., Anal. Chim. Acta 493, 63 (2003). ELISA screening method: W. L. Shelver, D. J. Smith, J. Agric. Food Chem. 52, 2159 (2004).
Properties
mp 166°.Derivative
Hydrochloride.Nomenclature
CAS number: 119520-06-8;
186046-04-8
(monohydrate)
;
186046-05-9
(trihydrate)
Zilmax (Intervet). C14H19N3O2.HCl; mol wt 297.78.
C 56.47%, H 6.77%, N 14.11%, O 10.75%, Cl 11.91%.