12-00507. Amisometradine [Archived]

Nomenclature

CAS number: 550-28-7
6-Amino-3-methyl-1-(2-methyl-2-propenyl)-2,4(1H,3H)-pyrimidinedione; 6-amino-3-methyl-1-(2-methylallyl)uracil; 1-methallyl-3-methyl-6-aminotetrahydro-2,4-pyrimidinedione; 6-amino-1-methallyl-3-methylpyrimidine-2,4-dione; aminoisometradine; Rolicton (Searle).
C9H13N3O2; mol wt 195.22.
C 55.37%, H 6.71%, N 21.52%, O 16.39%.

Description and references

Prepn: Papesch, Schroeder, US 2729669 (1956 to Searle).

Chemical structure

Properties

Crystals, mp 175°. Soly in water (25°): 2.0 g/100 ml. Freely sol in alcohol, acetone; insol in ether.

Therapeutic Category

Diuretic.

Keywords

Diuretic; Uracils

Status

This monograph has been retired and is no longer subject to revision or update.