12-00620. Amphecloral [Archived]

Nomenclature

CAS number: 5581-35-1
α-Methyl-N-(2,2,2-trichloroethylidene)benzeneethanamine; α-methyl-N-(2,2,2-trichloroethylidene)phenethylamine; N-[2-(1-phenylpropyl)]-2,2,2-trichloroethylidenimine; amfecloral.
C11H12Cl3N; mol wt 264.58.
C 49.93%, H 4.57%, Cl 40.20%, N 5.29%.

Description and references

Prepn: Cavallito, US 2923661 (1960 to Irwin, Neisler).

Chemical structure

Derivative

dl-Form.

Properties

bp0.5 95°. nD25 1.530.

Derivative

d-Form.

Properties

[α]D +49.9±0.3° (c = 5 in dioxane).

Therapeutic Category

Anorexic.

Keywords

Anorexic

Status

This monograph has been retired and is no longer subject to revision or update.