12-00621. Amphenidone [Archived]

Nomenclature

CAS number: 134-37-2
1-(3-Aminophenyl)-2(1H)-pyridinone; 1-(m-aminophenyl)-2(1H)-pyridone.
C11H10N2O; mol wt 186.21.
C 70.95%, H 5.41%, N 15.04%, O 8.59%.

Description and references

Prepn: Scudi et al., US 2947754 (1960 to Wallace & Tiernan). Toxicity data: Plekss et al., Fed. Proc. 19, 390 (1960).

Chemical structure

Properties

Crystals, mp 182.5-184.5°. LD50 in mice, rats (mg/kg): 1300, 3200 orally (Plekss).

Therapeutic Category

Sedative; hypnotic.

Keywords

Sedative/Hypnotic

Status

This monograph has been retired and is no longer subject to revision or update.