12-02674. Cryptenamine Tannates [Archived]

Nomenclature

Unitensen Tannate (Wallace Labs.).

Description and references

A prepn of ester alkaloids from Veratrum viride Ait., Liliaceae, obtained by non-aqueous benzene-triethylamine extraction process: Cavallito, US 2789977 (1957 to Irwin, Neisler). Contains hypotensive alkaloids protoveratrines A and B, germitrine, neogermitrine, germerine, germidine; also jervine, rubijervine, isorubijervine, germbudine: Kupchan, Gruenfeld, J. Am. Pharm. Assoc. 48, 727 (1959).

Properties

Cryptamine tannate is a tan, amorphous powder. Sol in alcohol and slightly sol in water.

Derivative

Cryptenamine.

Properties

Itself is a white, amorphous powder which induces sneezing. Practically insol in water. Freely sol in alcohol. Readily sol in dil acid soln. [α]D25 25 to 40° (ethanol).

Therapeutic Category

Antihypertensive.

Keywords

Antihypertensive

Status

This monograph has been retired and is no longer subject to revision or update.