Nomenclature
CAS number: 15687-22-6
6,7-Dihydroxy-4-(4-morpholinylmethyl)-2
H-1-benzopyran-2-one; 6,7-dihydroxy-4-(morpholinomethyl)coumarin; 4-morpholinomethylescutol; pholescutol.
C
14H
15NO
5; mol wt 277.27.
C 60.64%, H 5.45%, N 5.05%, O 28.85%.
Description and references
Prepn by the reaction of 4-chloromethyl-6,7-dihydroxycoumarin
with morpholine: FR M2035 (1963 to Labs. Dausse), C.A. 60, 4113 (1964). Pharmacological study:
J. P. Tarayre et al., Ann. Pharm.
Fr. 33, 467 (1975).
Properties
Crystals from 50% ethanol, mp 232°.Derivative
Hydrochloride.
Nomenclature
CAS number: 36002-19-4
LD-2988; Covalan (Dausse).
C
14H
15NO
5.HCl; mol wt 313.73.
C 53.60%, H 5.14%, N 4.46%, O 25.50%, Cl 11.30%.
Properties
Crystals from 75% ethanol, mp 259-261°.Therapeutic Category
Capillary protectant.
Keywords
Vasoprotectant
Status
This monograph has been retired and is no longer subject
to revision or update.