12-04375. Ganglefene [Archived]

Nomenclature

CAS number: 299-61-6
4-(2-Methylpropoxy)benzoic acid 3-(diethylamino)-1,2-dimethylpropyl ester; p-isobutoxybenzoic acid 3-(diethylamino)-1,2-dimethylpropyl ester; 1,2-dimethyl-3-diethylaminopropyl p-isobutoxybenzoate; p-isobutoxybenzoic acid α,β-dimethyl-γ-diethylaminopropyl ester.
C20H33NO3; mol wt 335.48.
C 71.60%, H 9.91%, N 4.18%, O 14.31%.

Description and references

Prepn: A. L. Mndzhoyan et al., SU 115905 (1958), C.A. 53, 17439a (1959). Pharmacologic studies: M. G. Udel'nov et al., Farmakol. Toksikol. 36, 299 (1973), C.A. 79, 61442y (1973); V. A. Gusel, Pharmacol. Biochem. Behav. 2, 1 (1974), C.A. 81, 114675b (1974). Stability study: V. G. Belikov et al., Khromatogr. Metody Farm. 1977, 42, C.A. 88, 141588 (1978).

Chemical structure

Derivative

Hydrochloride.
C20H33NO3.HCl; mol wt 371.94.
C 64.58%, H 9.21%, N 3.77%, O 12.90%, Cl 9.53%.

Therapeutic Category

Vasodilator (coronary).

Keywords

Vasodilator (Coronary)

Status

This monograph has been retired and is no longer subject to revision or update.