12-04774. Homofenazine [Archived]

Nomenclature

CAS number: 3833-99-6
Hexahydro-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-1H-1,4-diazepine-1-ethanol; 1-(β-hydroxyethyl)-4-[3-(2-trifluoromethylphenothiazin-10-yl)propyl]hexahydro-1,4-diazepine; 1-(2-hydroxyethyl)-4-[3-(3-trifluoromethylphenothiazin-10-yl)propyl]homopiperazine; 3-trifluoromethyl-10-[3-[4-(2-hydroxyethyl)homopiperazino]propyl]phenothiazine.
C23H28F3N3OS; mol wt 451.55.
C 61.18%, H 6.25%, F 12.62%, N 9.31%, O 3.54%, S 7.10%.

Description and references

Prepn: Schuler et al., US 3040043 (1962 to Degussa).

Chemical structure

Properties

bp1 230-240°.

Derivative

Dihydrochloride.

Nomenclature

CAS number: 1256-01-5
Pasaden (Asta).
C23H28F3N3OS.2HCl; mol wt 524.47.
C 52.67%, H 5.77%, F 10.87%, N 8.01%, O 3.05%, S 6.11%, Cl 13.52%.

Derivative

Difumarate.

Nomenclature

CAS number: 3093-71-8
C23H28F3N3OS.2C4H4O4; mol wt 683.69.
C 54.46%, H 5.31%, F 8.34%, N 6.15%, O 21.06%, S 4.69%.

Properties

Crystals, mp 148°.

Therapeutic Category

Sedative.

Keywords

Sedative/Hypnotic

Status

This monograph has been retired and is no longer subject to revision or update.