12-05831. Medibazine [Archived]

Nomenclature

CAS number: 53-31-6
1-(1,3-Benzodioxol-5-ylmethyl)-4-(diphenylmethyl)piperazine; 1-(diphenylmethyl)-4-piperonylpiperazine; 1-benzhydryl-4-piperonylpiperazine.
C25H26N2O2; mol wt 386.49.
C 77.69%, H 6.78%, N 7.25%, O 8.28%.

Description and references

Prepn: BE 616371; Regnier et al., US 3119826 (1962, 1964, both to Science Union). Pharmacology: Laubie et al., Arch. Int. Pharmacodyn. Ther. 151, 313 (1964); Laubie, Schmitt, ibid. 155, 1 (1965).

Chemical structure

Derivative

Dihydrochloride.

Nomenclature

CAS number: 96588-03-3
Vialibran (Servier).
C25H26N2O2.2HCl; mol wt 459.41.
C 65.36%, H 6.14%, N 6.10%, O 6.97%, Cl 15.43%.

Properties

Solid, mp 288°.

Therapeutic Category

Vasodilator (coronary); bronchodilator.

Keywords

Bronchodilator; Vasodilator (Coronary)

Status

This monograph has been retired and is no longer subject to revision or update.