12-05823. Mecloxamine [Archived]

Nomenclature

CAS number: 5668-06-4
2-[1-(4-Chlorophenyl)-1-phenylethoxy]-N,N-dimethyl-1-propanamine; 2-[(p-chloro-α-methyl-α-phenylbenzyl)oxy]-N,N-dimethylpropylamine; β-dimethylaminoisopropyl 4-chloro-α-methylbenzhydryl ether.
C19H24ClNO; mol wt 317.85.
C 71.80%, H 7.61%, Cl 11.15%, N 4.41%, O 5.03%.

Description and references

Prepn: GB 875060 (1960 to Astra Werke). Has been used as a component in sedative preparations.

Chemical structure

Properties

bp0.6 154-160°.

Derivative

Citrate.
C19H24ClNO.C6H8O7; mol wt 509.98.
C 58.88%, H 6.32%, Cl 6.95%, N 2.75%, O 25.10%.

Properties

Crystals, mp 120-124°.

Status

This monograph has been retired and is no longer subject to revision or update.