12-05839. Medrylamine [Archived]

Nomenclature

CAS number: 524-99-2
2-[(4-Methoxyphenyl)phenylmethoxy]-N,N-dimethylethanamine; 2-(p-methoxy-α-phenylbenzyloxy)-N,N-dimethylethylamine; 4-methoxy-Benadryl; p-methoxybenzhydryl β-dimethylaminoethylether; β-(p-methoxybenzhydryloxy)ethyldimethylamine; phenyl-p-methoxyphenylcarbinyl dimethylaminoethyl ether; Histaphen(e) (UCB); Postafen Salve (UCB).
C18H23NO2; mol wt 285.38.
C 75.76%, H 8.12%, N 4.91%, O 11.21%.

Description and references

Prepn: Morren, US 2668856 (1954 to U.C.B.).

Chemical structure

Derivative

Hydrochloride.
C18H23NO2.HCl; mol wt 321.84.
C 67.17%, H 7.52%, N 4.35%, O 9.94%, Cl 11.02%.

Properties

Crystals, mp 141°.

Therapeutic Category

Antihistaminic.

Keywords

Antihistaminic; Aminoalkylethers

Status

This monograph has been retired and is no longer subject to revision or update.