13-05823. Mefexamide [Archived]

Nomenclature

CAS number: 1227-61-8
N-[2-(Diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide; (p-methoxyphenoxy)acetic acid N-[2-(diethylamino)ethyl]amide; mexephenamide; NP-297; Mefexadyne (Anphar-Rolland); Timodyne.
C15H24N2O3; mol wt 280.36.
C 64.26%, H 8.63%, N 9.99%, O 17.12%.

Description and references

Prepn: Thuillier, Rumpf, Bull. Soc. Chim. Fr. 1960, 1786. Pharmacology: Thuillier, Arzneim.-Forsch. 14, 556 (1964). Clinical study in psychiatric patients: V. Faust et al., Schweiz. Rundsch. Med. Prax. 61, 1177 (1972).

Chemical structure

Derivative

Hydrochloride.
C15H25ClN2O3; mol wt 316.82.
C 56.87%, H 7.95%, Cl 11.19%, N 8.84%, O 15.15%.

Properties

mp 112°.

Therapeutic Category

CNS stimulant.

Keywords

CNS Stimulant

Status

This monograph has been retired and is no longer subject to revision or update.