12-05915. Mercamphamide [Archived]
Nomenclature
CAS number: 127-50-4
3-[[3-(Hydroxymercuri)-2-methoxypropyl]carbamoyl]-1,2,2-trimethylcyclopentanecarboxylic
acid; N-[3-(hydroxymercuri)-2-methoxypropyl]camphoramic
acid; N-(γ-hydroxymercuri-β-methoxy)propylcamphoramic
acid. C14H25HgNO5; mol wt 487.94.
C 34.46%, H 5.16%, Hg 41.11%, N 2.87%, O 16.39%.
Description and references
Prepn: Molnar, US 2117901 (1938); Werner, Scholz, J. Am. Chem. Soc. 76, 2453 (1954).
Derivative
Sodium salt.Nomenclature
CAS number: 124-82-3
C14H24HgNNaO5; mol wt 509.92.
C 32.98%, H 4.74%, Hg 39.34%, N 2.75%, Na 4.51%, O 15.69%.
Properties
Prepd as a mixture of 20% of the free acid plus 80% of the sodium salt. Mixture contains about 40% Hg and is described as a white, bitter powder; very slightly sol in water or ether; sol in alcohol and dil solns of sodium hydroxide. An aq suspension is practically neutral. pH about 8.Derivative
Mixture of sodium salt with theophylline.Nomenclature
CAS number: 8012-34-8
Mercurophyllin; Novurit (Chinoin). Therapeutic Category
Diuretic.
Keywords
Diuretic; Organomercurials
Status
This monograph has been retired and is no longer subject to revision or update.