12-06011. Methallatal [Archived]

Nomenclature

CAS number: 115-56-0
5-Ethyldihydro-5-(2-methyl-2-propenyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione; 5-ethyl-5-(2-methylallyl)-2-thiobarbituric acid; ethyl-β-methylallylthiobarbituric acid; V-12; Mosidal.
C10H14N2O2S; mol wt 226.30.
C 53.07%, H 6.24%, N 12.38%, O 14.14%, S 14.17%.

Description and references

Prepn: Volwiler, Tabern, US 2153729 (1939 to Abbott).

Chemical structure

Properties

Crystals, mp 160-161°. Insol in water. Forms an alkaline sodium salt which is sol in water, alcohol.

Note

This is a controlled substance (depressant): 21 CFR, 1308.13.

Therapeutic Category

Antiemetic.

Keywords

Antiemetic

Status

This monograph has been retired and is no longer subject to revision or update.