12-09030. Subathizone [Archived]

Nomenclature

CAS number: 121-55-1
2-[[4-(Ethylsulfonyl)phenyl]methylene]hydrazinecarbothioamide; p-ethylsulfonylbenzaldehyde thiosemicarbazone; 4-ethylsulfonylbenzaldehyde 3-thiosemicarbazone; Ethizone.
C10H13N3O2S2; mol wt 271.36.
C 44.26%, H 4.83%, N 15.49%, O 11.79%, S 23.63%.

Description and references

Prepn from 4-ethylsulfonyltoluene: Bernstein et al., J. Am. Chem. Soc. 73, 906 (1951); other prepns are described in JP 52 1119 (1952); US 2621484 (1952 to Schenley).

Chemical structure

Properties

Crystals from aq n-propanol, mp 234-235° (dec).

Therapeutic Category

Antibacterial (tuberculostatic).

Keywords

Antibacterial (Tuberculostatic)

Status

This monograph has been retired and is no longer subject to revision or update.