12-09117. Sulfatolamide [Archived]

Nomenclature

CAS number: 1161-88-2
4-Amino-N-(aminothioxomethyl)benzenesulfonamide compd with 4-(aminomethyl)benzenesulfonamide (1:1); 1-sulfanilyl-2-thiourea compd with α-amino-p-toluenesulfonamide; α-amino-p-toluenesulfonamide salt with 1-sulfanilyl-2-thiourea; 4-homosulfanilamide salt with 1-sulfanilyl-2-thiourea; 1-sulfanilylthiocarbamide salt with 4-aminomethylbenzenesulfonamide; Marbadal (Hartmann).
C14H19N5O4S3; mol wt 417.53.
C 40.27%, H 4.59%, N 16.77%, O 15.33%, S 23.04%.

Description and references

Prepn: Behnisch, Klarer, US 2696454 (1954 to Schenley Ind.).

Chemical structure

Properties

Crystals, mp 179-181°. Slightly sol in water (to 0.78%) with neutral reaction. Freely sol in dil hydrochloric acid; sol in dil sodium hydroxide and ammonia; slightly sol in alcohol and acetone. Practically insol in ether.

Therapeutic Category

Antibacterial.

Keywords

Antibacterial (Synthetic); Sulfonamides

Status

This monograph has been retired and is no longer subject to revision or update.