12-09596. Tiomesterone [Archived]

Nomenclature

CAS number: 2205-73-4
(1α,7α,17β)-1,7-Bis(acetylthio)-17-hydroxy-17-methylandrost-4-en-3-one; 17β-hydroxy-1α,7α-dimercapto-17-methylandrost-4-en-3-one 1,7-diacetate; 1α,7α-bis(acetylthio)-17α-methyltestosterone; 1α,7α-bis(acetylmercapto)-17α-methyltestosterone; thiomesterone; STA-307; Emdabolin (Chugai); Protabol (Draco).
C24H34O4S2; mol wt 450.65.
C 63.96%, H 7.60%, O 14.20%, S 14.23%.

Description and references

Prepn: Krmer, Ber. 96, 2803 (1963); Brueckner et al., US 3087942 (1963 to E. Merck).

Chemical structure

Properties

Crystals, mp 205-206°. [α]D 66° (dioxane). uv max: 237.5 nm (ε 19800).

Therapeutic Category

Androgen.

Keywords

Androgen

Status

This monograph has been retired and is no longer subject to revision or update.