13-09529. Tiocarlide [Archived]

Nomenclature

CAS number: 910-86-1
N,N′-[4-(3-Methylbutoxy)phenyl]thiourea; 4,4′-bis(isopentyloxy)thiocarbanilide; 4,4′-di(isoamyloxy)thiocarbanilide; 1,3-bis(p-isoamyloxyphenyl)-2-thiourea; thiocarlide; DATC; Datanil (Wander); Disocarban (Chem. Berlin); Isoxyl (Continental Pharma).
C23H32N2O2S; mol wt 400.58.
C 68.96%, H 8.05%, N 6.99%, O 7.99%, S 8.00%.

Description and references

Prepn: Buu-Hoi, Xuong, Compt. Rend. 237, 498 (1953); Huebner, Scholz, US 2703815 (1955 to Ciba).

Chemical structure

Properties

Crystals from ethanol, mp 134-145°.

Therapeutic Category

Antibacterial (tuberculostatic).

Keywords

Antibacterial (Tuberculostatic)

Status

This monograph has been retired and is no longer subject to revision or update.