13-00253. Alkofanone [Archived]

Nomenclature

CAS number: 7527-94-8
3-[(4-Aminophenyl)sulfonyl]-1,3-diphenyl-1-propanone; 3-phenyl-3-sulfanilylpropiophenone; p-aminophenyl(2-benzoyl-1-phenylethyl)sulfone; Nu-404; Ro-2-0404; Alfone.
C21H19NO3S; mol wt 365.45.
C 69.02%, H 5.24%, N 3.83%, O 13.13%, S 8.77%.

Description and references

Prepn: Goldberg et al., Jubilee Volume Emil Barell (Basle, 1946) p 341; Goldberg, US 2421836 (1947 to Hoffmann-La Roche).

Chemical structure

Properties

Decomp 221-223°. Slightly soluble in acetone, dioxane. Practically insol in most of the common organic solvents.

Therapeutic Category

Antidiarrheal.

Keywords

Antidiarrheal

Status

This monograph has been retired and is no longer subject to revision or update.