13-00383. Ambucaine [Archived]

Nomenclature

CAS number: 119-29-9
4-Amino-2-butoxybenzoic acid 2-diethylaminoethyl ester; 2-butoxy-4-aminobenzoic acid β-diethylaminoethyl ester; β-diethylaminoethyl 2-butoxy-4-aminobenzoate; 2-diethylaminoethyl 4-amino-2-n-butoxybenzoate; ambutoxate.
C17H28N2O3; mol wt 308.42.
C 66.20%, H 9.15%, N 9.08%, O 15.56%.

Description and references

Prepn: Büchi et al., Helv. Chim. Acta 34, 1002 (1951); Clinton et al., J. Am. Chem. Soc. 74, 592 (1952); Clinton, Laskowski, US 2689248 (1954 to Sterling Drug); Grimme, Schmitz, Ber. 87, 179 (1954).

Chemical structure

Derivative

Hydrochloride.

Nomenclature

CAS number: 5870-25-7
Win-3706; Sympocaine (Winthrop).
C17H28N2O3.HCl; mol wt 344.88.
C 59.20%, H 8.48%, N 8.12%, O 13.92%, Cl 10.28%.

Properties

Crystals, mp 127°.

Derivative

Dihydrochloride.

Properties

Crystals, decomp 156.8-159°.

Therapeutic Category

Anesthetic (local).

Keywords

Anesthetic (Local)

Status

This monograph has been retired and is no longer subject to revision or update.