12-00403. Ambucetamide [Archived]

Nomenclature

CAS number: 519-88-0
α-(Dibutylamino)-4-methoxybenzeneacetamide; α-dibutylamino-α-(p-methoxyphenyl)acetamide; α-p-methoxyphenyl-α-di-n-butylaminoacetamide; A-16.
C17H28N2O2; mol wt 292.42.
C 69.82%, H 9.65%, N 9.58%, O 10.94%.

Description and references

Antispasmodic. Prepn starting with dibutylamine, anisaldehyde and potassium cyanide: Janssen, J. Am. Chem. Soc. 76, 6192 (1954).

Chemical structure

Properties

Rods from ethanol + 10% ether. mp 134° (first reported as mp 125-127°). Practically insol in water. Sol in ethanol, isopropanol, glacial acetic acid.

Status

This monograph has been retired and is no longer subject to revision or update.