Nomenclature
CAS number: 305-97-5
Mercaptobutanedioic acid antimony(3+) lithium salt (3:1:6); 2,2′,2′′-[stibilidynetris(thio)]trisbutanedioic acid hexalithium
salt; mercaptosuccinic acid antimonate (III) hexalithium salt; mercaptosuccinic acid
S-antimony derivative lithium
salt; lithium antimoniothiomalate; lithium antimony thiomalate; Anthiomaline (Specia).
C
12H
9Li
6O
12S
3Sb; mol wt 604.79.
C 23.83%, H 1.50%, Li 6.89%, O 31.75%, S 15.91%, Sb 20.13%.
Sb.(C
4H
6O
4S)
3.6Li.
Description and references
Prepn: M. Delépine, P. Gailliot, US 2060181 (1936 to Rhne-Poulenc). Antitrypanosomal activity: N. Ercoli et al., Chemotherapy (Basel) 26, 254 (1980). Therapeutic use in buffaloes: R. K. Gupta, S. P. Pachauri, Agric. Sci. Dig. 2, 65 (1982);
V. Kumar et al., J. Vet. Parasitol. 3, 125 (1989). HPLC determn in biological fluids: N.
A. El-Rabbat et al., Talanta 37, 951 (1990); titrimetric determn: F. Belal et
al., Microchem. J. 44, 296 (1991).
Derivative
Enneahydrate.
Properties
White hygroscopic powder. Very soluble in water;
very slightly sol in alcohol, ether.Therapeutic Category
Anthelmintic (Trematodes).
Therapeutic Category (Veterinary)
Anthelmintic.
Keywords
Anthelmintic (Trematodes)
Status
This monograph has been retired and is no longer subject
to revision or update.