13-00771. Aramite (Uniroyal) [Archived]

Nomenclature

CAS number: 140-57-8
Sulfurous acid 2-chloroethyl 2-[4-(1,1-dimethylethyl)phenoxy]-1-methylethyl ester; sulfurous acid 2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethyl ester; 2-chloroethyl 1-methyl-2-(p-tert-butylphenoxy)ethyl sulfite; 2-(p-tert-butylphenoxy)isopropyl 2-chloroethyl sulfite; β-chloroethyl β-(p-tert-butylphenoxy)-α-methylethyl sulfite; compd 88R; ENT-16519; Niagaramite (FMC).
C15H23ClO4S; mol wt 334.86.
C 53.80%, H 6.92%, Cl 10.59%, O 19.11%, S 9.58%.

Description and references

Prepn: Harris et al., US 2529494 (1950 to U.S. Rubber). Toxicology: B. L. Oser, M. Oser, Toxicol. Appl. Pharmacol. 2, 441 (1960). Carcinogenicity studies: eidem, ibid. 4, 70 (1962); Truhaut et al., C.R. Seances Acad. Sci. Ser. D 281, 599 (1975).

Chemical structure

Properties

Liquid. d 1.1450 to 1.1620. mp 31.7°. bp0.1 175°; bp7.0 200-210°. Vapor tension at 25°: <10 mm. nD20 1.5100 to 1.5118; nD27 1.5075. Practically insol in water. Misc with many organic solvents. Soly in petroleum oils decreases rapidly with decreasing temperatures. LD50 orally in rats: 3.90±0.28 g/kg (Oser, Oser).

Caution

Direct contact with undiluted form or concentrated solutions may cause irritation of skin and conjunctiva. See: Clinical Toxicology of Commercial Products, R. E. Gosselin et al., Eds. (Williams & Wilkins, Baltimore, 5th ed., 1984) Section II, p 289. This substance has been listed as reasonably anticipated to be a carcinogen: Fourth Annual Report on Carcinogens (NTP 85-002, 1985) p 26; delisted because no U.S. residents exposed: Fifth Annual Report on Carcinogens (NTP 89-239, 1989) p 340.

Use

Miticide.

Status

This monograph has been retired and is no longer subject to revision or update.