13-00799. Arsacetin [Archived]

Nomenclature

CAS number: 618-22-4
[4-(Acetylamino)phenyl]arsonic acid; p-acetamidobenzenearsonic acid; N-acetyl-p-aminobenzenearsonic acid; N-acetylarsanilic acid.
C8H10AsNO4; mol wt 259.09.
C 37.09%, H 3.89%, As 28.92%, N 5.41%, O 24.70%.

Description and references

Prepn of free acid and sodium salt: Bart, Ann. 429, 55 (1922). Toxicity: A. Gros, Biochem. Z. 184, 360 (1927).

Chemical structure

Derivative

Sodium salt tetrahydrate.
C8H9AsNNaO4.4H2O; mol wt 353.13.
C 27.21%, H 4.85%, As 21.22%, N 3.97%, Na 6.51%, O 36.25%.

Properties

Cryst powder. Poisonous! One gram dissolves in 10 ml cold water, 3 ml hot water. LD50 i.v. in rabbits: 550 mg/kg (Gros).

Note

Sodium salt was formerly referred to as arsacetin.

Therapeutic Category

Sodium salt formerly as antisyphilitic.

Keywords

Antisyphilitic

Status

This monograph has been retired and is no longer subject to revision or update.